The common antibiotic doxycycline can disrupt the formation of negative associations in the brain, according to new research from UCL and the University of Zurich.

The study, published in Molecular Psychiatry, was a pre-registered, placebo-controlled, double-blind randomised controlled trial in 76 healthy volunteers.

In the first session, participants were given either doxycycline or a placebo and learnt to associate a certain colour with an electric shock. A week later they were shown the colours again, accompanied by a loud sound but no shocks, and their fear responses were measured.*

Read more at University College London